Full Study Name

ISO – Investigation of Segmental Overgrowth Disorders

Lead Site


Local Principal Investigator

Professor Jill Clayton-Smith

Study Status


Main Aims

To investigate the range of metabolic and growth phenotypes of patients with rare segmental overgrowth disorders, hemihypertrophy and lipoblastomas, and identify the genetic aetiology of these conditions.

Inclusion Criteria
  • Segmental overgrowth OR
  • Lipoblastoma OR
  • Hemihypertrophy AND
  • Clinically stable enough to undergo testing safely
Exclusion Criteria
  • Pregnant or breastfeeding
  • Any current medical disorder or medication likely to impair ability to follow the study protocol safely and effectively
  • Incapacity to give informed consent
Open Sites

Lead Site: Cambridge. Exeter, Oxford, Newcastle, MFT, St George’s, Leicester, Sheffield

For more information click here