Full Study Name

IMAGINE – Intellectual Disability and Mental Health: Assessing Genomic Impact on Neurodevelopment

Lead Site


Local Principal Investigator

Professor Jill Clayton-Smith

Study Status


Main Aims

Open to patients with intellectual disability (who have a change in their genetic code) to find out which features are common to individuals with the same condition and which features reflect the individual differences between people.

Inclusion Criteria
  • Diagnosed with an intellectual disability
  • Had a diagnostic microarray analysis of DNA by an accredited laboratory
  • Is 3-18 years of age
  • Has at least one CNV/SNV reported as being clinically significant or a pathological sequence variant
  • Is willing to participate
Exclusion Criteria

Those individuals not matching the above inclusion criteria.

Open Sites

Lead Site: Cambridge. Birmingham, Bristol, Cardiff, Exeter, GOSH, Guy’s, Leeds, Leicester, Liverpool, Newcastle, North West London, Nottingham

Oxford, Sheffield, Southampton, St George’s, St Marys Hospital – Manchester

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