Immunology and Rheumatology

The immunology and rheumatology research at MCGM involves strong collaboration between clinical genomics, paediatric and adult immunology and rheumatology at the trust and the university. The research undertaken focuses on conditions in which the immune system is overactive (autoimmune or autoinflammatory diseases), or those in which the anticipated immune response is insufficient (immunodeficiency). The research covers a range of conditions affecting the immune system, and includes gene discovery and functional studies, along with natural history studies. The aim of the research is to enhance diagnosis of rare immune disease, improve understanding of conditions to guide management and ultimately undertake clinical trials in rare disease in Manchester.

The work in this group overlaps with that of Professor Newman and Dr Banka at MCGM with regards to cytopenias for example, and there is significant collaboration within the department.