Neurofibromatosis Type 2

Neurofibromatosis Type 2 (NF2) is a variable genetic condition which causes benign tumours in the nerves coming from the brain and spinal cord and on the surrounding tissues called meninges. The hallmark feature of NF2 is the presence of bilateral tumours on the hearing and balance nerves called Vestibular Schwannomas.  About half of patients have an affected parent and half of patients have a new mutation. The Manchester genetics laboratory has facilities for diagnostic and predictive testing for NF2.

Manchester is one of four specialist nationally commissioned centres in England where NF2 is managed. Professor Gareth Evans is the national lead for the NF2 service.  Referrals can be made directly by writing to Professor Evans. The MDT coordinator, Kirsty Henshaw, can be contacted with any queries on 0161 276 5152.

The joint speciality clinic for NF2 has been established to offer health care for patients and their families who have a diagnosis of NF2. As there may be a number of doctors involved in caring for people with NF2, a multidisciplinary approach is the best for explaining the diagnosis, assessing symptoms and deciding what treatment, if any, should be offered.  These decisions are complicated and need careful consideration by the specialist team.