We simultaneously sequence 27 genes known to cause inherited arrhythmia/cardiac arrest. We provide a comprehensive scientific interpretation of variants found and issue a report summarising our findings.
For individuals with resuscitated (ventricular fibrillation) cardiac arrest without known aetiology. On identification of a pathogenic change in an index case presymptomatic testing of relatives can be offered. Referrals for testing are only accepted from a Consultant Cardiologist or a Consultant Clinical Geneticist (please contact the Clinical Genetics department for specific information). Referrals should be accompanied by a clinical diagnosis and details of family history. Referrals should also be accompanied by a completed standard referral form available in the Referral Forms section. For optimal results please send a fresh EDTA blood sample (1-4ml) or a minimum of 5µg of extracted DNA. For a full list of genes included in the assay please contact the laboratory.
Price & reporting times
Please contact the laboratory for prices.
|Test||Price (NHS)||Price (non-NHS)||TRT|
|Arrhythmia/Cardiac Arrest (27 gene) panel||POA||POA||112cd|
Test validation & quality assurance - information for users
4ml EDTA blood sample
Please see our referral guidelines for more information.
OMIM Number(s) - 601439, 604001, 106410, 114205, 114204, 600003, 114180, 114251, 611778, 605206, 176261, 603796, 604433, 152427, 600681, 600734, 607542, 180902, 602861, 600235, 608214, 608256, 600163, 604427, 601017, 603283, 606936
Gene(s) - ABCC9, AKAP9, ANK2, CACNA1C, CACNA2D1, CACNB2, CALM1, CASQ2, GPD1L, HCN4, KCNE1, KCNE2, KCNE3, KCNH2, KCNJ2, KCNJ5, KCNQ1, RYR2, PKP2, SCN1B, SCN3B, SCN4B, SCN5A, SCN10A, SNTA1, TRDN, TRPM4