Biochemical Genetics - Home Page

The Willink Biochemical Genetics Unit is based at the Royal Manchester Children's Hospital. Close integration of laboratory investigation and clinical management within the Unit has led to the development of a unique service aimed at the prevention of mental retardation by the early diagnosis and appropriate management of children and adults affected by inherited biochemical defects.

The Unit is housed in a purpose-built building completed in 1985. Ground floor accommodation includes the clinic area and office suite. The first floor contains the laboratories responsible for the Region's newborn screening programme as well as a wide range of biochemical and molecular investigations. There is very close liaison between the clinicians and scientists responsible for the service.

Clinical interpretation of results is essential when investigating for rare disorders. Clinicians sending samples are contacted personally about their patients when positive or important negative diagnoses are made. Three consultant paediatricians provide a 24-hour on-call service for metabolic patients. Advice regarding investigations is available at all times by contacting the paediatricians, the consultant clinical scientist or other senior scientists in the laboratory.

There are a number of specialist metabolic clinics held each week. All clinics are consultant-led and patients are seen initially by the consultant staff. The medical staff are supported by specialist nurses based in the Unit, the hospital's Chief Dietician and a senior Clinical Psychologist. In-patients are managed on Ashby Ward at the Royal Manchester Children's Hospital, a facility shared with the Paediatric Neurology service.

Click here to download the Willink Biochemical Genetics Unit Handbook